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Pablo Villoslada (UNAV)

Pablo Villoslada, director of the Multiple Sclerosis Center at the Department of Neurology and Neuroimmunology Lab (UNAV), Consultant Neurologist of the Department of Neurology, Clinica Universitaria de Navarra and Assistant Professor, University of Navarra. He received his PhD in neuroscience at the Autonomous University of Barcelona (1996).

He has some 30 international publications on neuroimmunology, immunology, genetics, system biology and clinical aspects of Multiple Sclerosis (MS). Invited speaker of national and international meetings and workshops. Member of the Spanish Neurological Society (SEN), American Academy of Neurology (AAN), International Society of Neuroimmunology (ISNI) and International Society of Computational Biology (ISCB).

The University of Navarra is an experienced centre in biomedical research using animal models, cellular and molecular immunology and neurobiology. Dr Villoslada pioneered applying complexity science to neurology and is active in a bioinformatic and systems biology group composed of 3 professors of mathematics and 4 PhD students with expertise in Bayesian reverse engineering, mathematical modelling, network analysis and system biology studies. All equipment required to develop the research program is currently operative in his institute. His work is based on animal models and in human vitro models of multiple sclerosis gene and protein networks and phenotypic analysis. Important features are analysis of network topology and dynamics in MS and developing a new in vitro system models to identify new diagnostic markers and therapeutic targets. This work has already resulted in a patented drug target in MS.

He has extensive national and international collaborations. An important part of this collaboration is that with professor Solé of the ICREA-Complex Systems Lab in Barcelona. He participated (2001-2005) in a NIH grant as investigator and has 3 grants from the Spanish Health and Science ministries (PI).

Key publications

Moreno B, Hevia H, Santamaria M, Sepulcre J, Munoz J, Garcia-Trevijano ER, Berasain C, Corrales FJ, Avila MA, Villoslada P. Methylthioadenosine reverses brain autoimmune disease. Ann Neurol. 2006 (in press)
Palacios R, Aguirrezabal I, Fernandez-Diez B, Brieva L, Villoslada P. Chromosome 5 and multiple sclerosis. J Neuroimmunol. 2005;167:1-3.

Page Manager: Johan Thompson|Last update: 11/20/2006

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