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Filippo Castiglione (CNR)

Filippo Castiglione, senior researcher at the Institute for Computing Applications (Rome) of the National Research Council (CNR). He received his PhD in Scientific Computing at the Univeristy of Cologne (Germany). He was a postdoc at the Institute for Medicine and Bio-Mathematics (Israel).

Filippo Castiglione research interests range from modelling of biological phenomena, simulation of the immune system and clinical applications, scientific and high-performance computing. He has published more than 30 scientific articles. Filippo Castiglione has been holding visiting/research positions at the University of Bielefeld (2001) and Harvard Medical School (2001-02).

Filippo Castiglione’s group at IAC has been modeling biological systems since 1998, thus gaining significant experience in the development of mathematical and computational models of biological phenomena based on stochastic cellular automata. The group collaborates with the Harvard Medical School for the study of cell signalling; the Institute for Medicine and Bio-mathematics (Israel) for the study of hypersensitive reactions; researchers and MDs of the Italian Institute for Infectious Disease “L. Spallanzani¿ in Rome for the study of the HIV-1 infection; the Policlinico Monteluce in Perugia (Italy) and Dipartimento di Patologia Sperimentale all'Università di Bologna (Italy) for the study of cancer vaccines and immunotherapies; the Molecular Genetics Group of the University of Rome “Tor Vergata¿ for the study of protein-protein interaction networks.

Key publications

Castiglione F, Toschi F, Bernaschi M, Succi S, Benedetti R, Falini B, et al. Computational modeling of the immune response to tumor antigens. J Theor Biol 2005; 237:390-400.
Castiglione F, Sleitser V, Agur Z. Analyzing hypersensitivity to chemotherapy in a Cellula Automata model of the immune system. In: Cancer Modeling and Simulation. London: Chapman & Hall/CRC Press 2003. p. 333-65.

Page Manager: Johan Thompson|Last update: 11/20/2006
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